Scientists are constantly discovering molecules that could help to promote human health. Some of these molecules are also meant to assist in achieving our best potential. MK-677 is a non-peptide molecule that has received a lot of attention, but the legality and safety raise concerns. Let’s take a look at what is MK 677 used for and consider the legality of the substance.
What is MK-677 Ibutamoren?
The compound MK-677, also known as Ibutamoren mesylate, stimulates the release of growth hormone (GH) and boosts insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the response of ghrelin, the hormone that stimulates hunger, and binding to one of the brain’s growth hormone secretagogue receptors (GHSR).
Ghrelin is primarily found in the digestive system. It sends the message to the brain when you’re hungry, alerting the body when it’s ready to consume food. When Ibutamoren is taken, it imitates ghrelin, activating the feeling of “craving” in several aspects. As Ibutamoren is emitted throughout the body, it triggers your appetite, pleasure, mood, memory, and awareness.
What Does MK-677 Do?
MK-677, also known as Ibutamoren, is a small-molecule drug that stimulates muscle growth and increases muscle mass. Classified as a non-peptide agonist, the drug has the capability to stimulate growth hormone and ghrelin receptors.
There’s a lot of controversy surrounding the drug, including the fact that it has been banned for use by major sports institutions. It’s also on the World Anti-Doping Agency’s Prohibited List.
What Are the Benefits of MK 677?
MK-677 has become particularly attractive to those who lead an active lifestyle, especially those who regularly visit the gym. The benefits, however, extend beyond the barriers of someone looking to improve their muscle and body mass. Some of the benefits of MK-677 (Ibutamoren) include the following:
Increased Muscle Growth
MK-677 is known for stimulating muscle growth and increasing muscle mass. While everyone’s body mass and exercise routine differ, some individuals may see more noticeable results and changes in their bodies than others. Bodybuilders and weightlifters are more likely to consume MK-677 to improve their performance and overall physique.
Improved Bone Density
A study showed that growth hormone (GH) increases bone turnover and stimulates osteoblast activity. “The administration of MK-677, an orally active GH secretagogue, together with alendronate, a potent inhibitor of bone resorption, would maintain a higher bone formation rate relative to that seen with alendronate alone, thereby generating greater enhancement of bone mineral density (BMD) in women with postmenopausal osteoporosis.”
Muscle Loss Prevention
Bodybuilders and weightlifters often experience and struggle with muscle loss at some point in their fitness journey. When taking MK-677 Ibutamoren, this is not something to worry about. MK-677 enhanced muscle growth while simultaneously preventing muscle loss.
Increased Energy and Endurance
MK-677, also known as Ibutamoren, has been reported to enhance physical performance and endurance through exercise. This boost of energy makes for a more efficient and dynamic workout.
Improved Sleep
Research shows that growth hormone (GH) and MK-677 (Ibutamoren) improve the quality and duration of sleep, as well as rapid eye movement (REM) sleep, and alter the relative growth hormone deficiency associated with senescence.
Improved Collagen
Studies have shown that Ibutamoren may improve hair and skin health. It may also help heal skin wounds and marks. Growth hormone (GH) stimulates cell transformation and production, as well as collagen synthesis and management.
Is MK-677 Safe?
The FDA has labeled MK-677 as an Investigational New Drug. It is typically sold only for research purposes and cannot be labeled as a supplement. The World Anti-Doping Agency (WADA) has banned MK-677 from most, if not all, significant sports—especially the Olympics.
This means the safety of the drug is questionable, and also why it’s not available as a therapeutic option in the United States. As investigations continue into the use of MK-677, it will shed more light on the long-term safety.
Side Effects of MK-677 Ibutamoren
The side effects of the drug may include:
- Muscle pain
- Joint pain
- Severe migraines and headaches
- Lack of energy
- Increased appetite
- Motivation loss
- Fluid retention
- Depression
- Increased stress and anxiety
Some studies that used human subjects also found a risk of increased fasting blood glucose, as well as elevated HbA1c levels. There’s also some evidence that shows the molecule may increase the risk of insulin resistance.
How Can Androgenix Help?
Androgenix focused on helping patients get personalized therapies and treatment programs. While MK 677 is not considered a legal substance, the experts at Androgenix can recommend several alternative options that may provide similar effects. At Androgenix, we can help you better understand your own body and gain insight into what you need to optimize your health.
Ready to start your journey? Reach out to schedule your consultation.
